SCHEMBL4785607

SCHEMBL4785607

Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCCC(=O)N(CCO)CCO.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCCC(=O)Nc1cnoc1C

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4204991 0.93 FASN (0.58) FASN
SCHEMBL4785603 0.92 FASN (0.47) FASN
SCHEMBL4199046 0.91 FASN (0.58) FASN
SCHEMBL4203880 0.83 FASN (0.60) FASN
SCHEMBL4196135 0.82 FASN (0.59) FASN
SCHEMBL4201394 0.82 FASN (0.59) FASN
SCHEMBL4202327 0.81 FASN (0.63) FASN
SCHEMBL4198936 0.81 FASN (0.58) FASN
SCHEMBL4195170 0.80 FASN (0.61) FASN
SCHEMBL4197717 0.80 FASN (0.60) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed