Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526764 | 0.84 | RXFP1 (0.55) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL4785651 | 0.83 | RXFP1 (0.51) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL12912267 | 0.78 | RXFP1 (0.64) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL4784590 | 0.77 | RXFP1 (0.59) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL15526692 | 0.77 | RXFP1 (0.59) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL15526835 | 0.76 | LRRK2 (0.57) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL15526870 | 0.74 | RXFP1 (0.60) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL12891166 | 0.73 | RXFP1 (0.59) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL15526662 | 0.73 | RXFP1 (0.74) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 | |
| SCHEMBL15526726 | 0.73 | RXFP1 (0.59) | RXFP1LRRK2CRHBPCRHR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069500-A1 | TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | disclosed |