Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 15/20 | 0.32 |
| ▸ | PLG | P00747 | 13/20 | 0.32 |
| ▸ | PLAT | P00750 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 6/20 | 0.32 |
| ▸ | F2 | P00734 | 5/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933056 | 0.90 | PTPN1 (0.44) | PTPN1PTPN2PLAUPLGPLAT | |
| SCHEMBL2929970 | 0.88 | PTPN1 (0.47) | PTPN1PTPN2 | |
| SCHEMBL3221264 | 0.81 | PTPN1 (0.47) | PTPN1PTPN2 | |
| SCHEMBL2930264 | 0.80 | PTPN1 (0.48) | PTPN1PTPN2 | |
| SCHEMBL3216007 | 0.79 | PTPN1 (0.47) | PTPN1PTPN2F10 | |
| SCHEMBL4557753 | 0.78 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL2933075 | 0.78 | PTPN1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL2934077 | 0.76 | PTPN1 (0.46) | PTPN1PTPN2 | |
| SCHEMBL3216895 | 0.76 | PTPN1 (0.45) | PTPN1PTPN2 | |
| SCHEMBL2934340 | 0.75 | PTPN1 (0.47) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008067527-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE FOR THE TREATMENT OF MUSCLE ATROPHY AND RELATED DISORDERS | NOVARTIS AG (CH) | 2008-06-05 | — | — | WO | disclosed |