Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | BACE1 | P56817 | 9/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511507 | 0.90 | BACE1 (0.42) | CNR1BACE1CTSDBACE2 | |
| SCHEMBL4517752 | 0.87 | CNR1 (0.38) | CNR1BACE1CTSDBACE2 | |
| SCHEMBL4513812 | 0.83 | CNR1 (0.38) | CNR1BACE1FAAH | |
| SCHEMBL4913957 | 0.83 | CNR1 (0.44) | CNR1BACE1CTSDBACE2 | |
| SCHEMBL4517959 | 0.82 | CNR1 (0.43) | CNR1BACE1FAAH | |
| SCHEMBL4523953 | 0.82 | CNR1 (0.43) | CNR1BACE1FAAH | |
| SCHEMBL4520613 | 0.79 | BACE1 (0.43) | CNR1BACE1CTSDBACE2FAAH | |
| SCHEMBL4115606 | 0.78 | CNR1 (0.51) | CNR1BACE1FAAH | |
| SCHEMBL20291002 | 0.78 | CNR1 (0.51) | CNR1BACE1FAAH | |
| SCHEMBL4785718 | 0.77 | CNR1 (0.46) | CNR1BACE1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |