Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747172 | 0.88 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL4786999 | 0.87 | TRPV1 (0.50) | TRPV1NTRK1 | |
| SCHEMBL4786503 | 0.85 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL3326550 | 0.85 | TRPV1 (0.64) | TRPV1 | |
| SCHEMBL2359657 | 0.83 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL3319311 | 0.83 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL4785630 | 0.81 | TRPV1 (0.48) | TRPV1NTRK1 | |
| SCHEMBL4785600 | 0.80 | TRPV1 (0.49) | TRPV1NTRK1 | |
| SCHEMBL3321468 | 0.79 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL4350196 | 0.78 | TRPV1 (0.66) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110863-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-09-18 | — | — | WO | claimed |
| WO-2008110863-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-09-18 | — | — | WO | disclosed |