Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.51 |
| ▸ | ACACA | Q13085 | 17/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255505 | 0.82 | ACACB (0.51) | ACACBACACAGAA | |
| SCHEMBL4263567 | 0.80 | ACACB (0.51) | ACACBACACAGAA | |
| SCHEMBL4255357 | 0.79 | ACACB (0.49) | ACACBACACAGAACYP1A2CYP2C9 | |
| SCHEMBL4252827 | 0.76 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL2210681 | 0.75 | ACACB (0.60) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL12510672 | 0.74 | ACACB (0.58) | ACACBACACAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL4254308 | 0.74 | ACACB (0.57) | ACACBACACA | |
| SCHEMBL4254216 | 0.73 | ACACB (0.59) | ACACBACACA | |
| SCHEMBL4259844 | 0.73 | ACACB (0.61) | ACACBACACA | |
| SCHEMBL3491416 | 0.72 | ACACB (0.60) | ACACBACACAKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121592-A2 | ACETYL COENZYME A CARBOXYLASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-09 | — | — | WO | claimed |