Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455066 | 0.94 | PTPN11 (0.49) | PTPN11NQO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL454957 | 0.88 | PTPN11 (0.50) | PTPN11NQO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL454499 | 0.80 | PTPN11 (0.49) | PTPN11NQO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL457343 | 0.76 | TP53 (0.52) | PTPN11NQO2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL455475 | 0.76 | GAA (0.50) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL4748264 | 0.76 | ERBB2 (0.53) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| Hydrochloric Acid SCHEMBL4748017 | 0.75 | ERBB2 (0.52) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL457180 | 0.74 | GAA (0.57) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL457327 | 0.73 | GAA (0.53) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| Hydrochloric Acid SCHEMBL4747848 | 0.73 | GAA (0.56) | NPC1RAB9ASMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |