SCHEMBL4786768

SCHEMBL4786768

Cc1c(-c2ncc(C3CCCCC3)o2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1.Cc1c(C(=O)NCC(=O)C2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.56
CNR2 P34972 13/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4787296 0.87 CNR1 (0.72) CNR1CNR2
SCHEMBL4787151 0.85 OPRL1 (0.52) CNR1CNR2
SCHEMBL4905874 0.75 CNR1 (0.75) CNR1CNR2
SCHEMBL4499547 0.73 CNR1 (1.00) CNR1CNR2
SCHEMBL6704796 0.73 CNR1 (1.00) CNR1CNR2
SCHEMBL4496279 0.72 CNR1 (1.00) CNR1CNR2
Dimethylamine SCHEMBL1040287 0.71 CNR1 (0.96) CNR1CNR2
SCHEMBL4786246 0.71
SCHEMBL4784644 0.71
SCHEMBL4786546 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008105607-A1 HETEROARYL-IMIDAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS GREEN CROSS CORPORATION (KR) 2008-09-04 WO disclosed