Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | GHSR | Q92847 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14424471 | 0.92 | EPHX1 (0.71) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL21237623 | 0.90 | EPHX1 (0.74) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL12362189 | 0.88 | EPHX1 (0.65) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL14424456 | 0.87 | HDAC1 (0.65) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4689241 | 0.87 | HDAC1 (0.64) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL7198019 | 0.86 | EPHX1 (0.63) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL7197441 | 0.86 | EPHX1 (0.63) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4785993 | 0.86 | EPHX1 (0.53) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4787348 | 0.86 | EPHX2 (0.55) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4786969 | 0.86 | EPHX2 (0.52) | EPHX1ALDH1A1HTTHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |