SCHEMBL4787124

SCHEMBL4787124

CCOC(=O)N1CCN(C(=O)Nc2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)ccc2C)CC1.Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)N1CCN(C(=O)C(C)C)CC1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4205258 0.94 FASN (0.62) FASN
SCHEMBL4196160 0.94 FASN (0.63) FASN
SCHEMBL14162041 0.85 FASN (0.53) FASN
SCHEMBL4733984 0.84 FASN (0.64) FASN
SCHEMBL4201080 0.84 FASN (0.67) FASN
SCHEMBL4202847 0.84 FASN (0.70) FASN
SCHEMBL4203366 0.84 FASN (0.63) FASN
SCHEMBL4196797 0.83 FASN (0.63) FASN
SCHEMBL4200430 0.83 FASN (0.62) FASN
SCHEMBL4201384 0.83 FASN (0.64) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed