Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930871 | 0.80 | MEN1 (0.52) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL6280416 | 0.80 | KMT2A (0.52) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL4352232 | 0.80 | MEN1 (0.52) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL11319289 | 0.78 | MEN1 (0.56) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL7034518 | 0.78 | MEN1 (0.50) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL12157084 | 0.77 | CYP19A1 (0.48) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL14149500 | 0.77 | CYP19A1 (0.70) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL19200293 | 0.77 | TSHR (0.55) | MEN1KMT2ACYP19A1TSHRESR1 | |
| SCHEMBL8760835 | 0.76 | SLC6A2 (0.48) | MEN1KMT2ACYP19A1NPSR1SLC6A2 | |
| SCHEMBL12224193 | 0.76 | KMT2A (0.60) | MEN1KMT2ACYP19A1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008083822-A1 | A CROSS-LINKING AGENT | BOREALIS TECHNOLOGY OY (FI) | 2008-07-17 | — | — | WO | claimed |
| WO-2008006563-A1 | PURINE DERIVATIVES AS A2A AGONISTS | NOVARTIS AG (CH) | 2008-01-17 | — | — | WO | disclosed |