Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292212 | 0.76 | BCHE (0.47) | BCHEHTTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9965045 | 0.74 | BCHE (0.49) | BCHEMAPTRECQLHTTNPC1 | |
| SCHEMBL21894060 | 0.72 | BCHE (0.47) | BCHEHTTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL964527 | 0.72 | BCHE (0.51) | BCHEHTTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL18255991 | 0.71 | BCHE (0.44) | BCHEHTTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28136861 | 0.71 | KCNH2 (0.44) | BCHESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7356165 | 0.71 | — | — | |
| SCHEMBL2631521 | 0.71 | BCHE (0.46) | BCHEHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4650922 | 0.70 | BCHE (0.42) | BCHEHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL21894061 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098859-A1 | HCV POLYMERASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-21 | — | — | WO | disclosed |