Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922817 | 0.88 | NPSR1 (0.52) | NPSR1F10F7MEN1KMT2A | |
| SCHEMBL4922803 | 0.88 | NPSR1 (0.52) | NPSR1F10F7MEN1KMT2A | |
| SCHEMBL4745316 | 0.85 | NPSR1 (0.58) | NPSR1SMN1; SMN2F10F7HSD17B10 | |
| SCHEMBL14045752 | 0.83 | NPSR1 (0.56) | NPSR1F10F7ALDH1A1CASR | |
| SCHEMBL4924403 | 0.82 | NPSR1 (0.53) | NPSR1F10F7HSD17B10MAPT | |
| SCHEMBL14067958 | 0.82 | NPSR1 (0.53) | NPSR1F10F7MEN1KMT2A | |
| SCHEMBL4924392 | 0.82 | NPSR1 (0.53) | NPSR1F10F7HSD17B10MAPT | |
| SCHEMBL4918662 | 0.82 | F10 (0.51) | NPSR1F10F7MEN1KMT2A | |
| SCHEMBL14025001 | 0.82 | NPSR1 (0.51) | NPSR1SMN1; SMN2F10F7HSD17B10 | |
| SCHEMBL4925156 | 0.82 | NPSR1 (0.51) | NPSR1SMN1; SMN2F10F7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109154-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |