SCHEMBL4787963

SCHEMBL4787963

Cc1ccc(-c2nc(CCOc3cccc(CN4CC[C@@H]4C(=O)O)c3)c(C)o2)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.56
PPARG P37231 19/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4880332 1.00 PPARA (0.56) PPARAPPARG
SCHEMBL4747144 0.94 PPARA (0.54) PPARAPPARG
SCHEMBL4746232 0.92 PPARG (0.57) PPARAPPARG
SCHEMBL14041184 0.92 PPARG (0.57) PPARAPPARG
SCHEMBL4853726 0.92 PPARA (0.54) PPARAPPARG
SCHEMBL4744736 0.91 PPARG (0.58) PPARAPPARG
SCHEMBL4744734 0.91 PPARG (0.58) PPARAPPARG
SCHEMBL4743984 0.90 PPARG (0.53) PPARAPPARG
SCHEMBL4746999 0.90 PPARG (0.53) PPARAPPARG
SCHEMBL4746305 0.90 PPARG (0.58) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008117982-A1 HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME CRYSTAL GENOMICS, INC. (KR) 2008-10-02 WO disclosed