Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ANPEP | P15144 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PPIA | P62937 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760 | 0.85 | KMT2A (0.67) | ALDH1A1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL23235729 | 0.84 | KMT2A (0.65) | ALDH1A1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL6033584 | 0.83 | TP53 (0.75) | ALDH1A1TP53GAASMN1; SMN2MAPT | |
| SCHEMBL22175600 | 0.79 | KMT2A (0.59) | ALDH1A1SMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL24568368 | 0.79 | MAPT (0.65) | ALDH1A1TP53SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL714625 | 0.79 | EPHX1 (0.77) | ALDH1A1TP53GAASMN1; SMN2KMT2A | |
| SCHEMBL12252067 | 0.79 | MAPT (0.69) | ALDH1A1TP53SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL11262217 | 0.79 | TP53 (0.64) | ALDH1A1TP53GAASMN1; SMN2MAPT | |
| SCHEMBL4788088 | 0.77 | MAPT (0.75) | ALDH1A1TP53SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL9781833 | 0.77 | TP53 (0.66) | TP53GAASMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119773-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |