Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852416 | 0.95 | TRPV1 (0.61) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL4785862 | 0.91 | TRPV1 (0.60) | TRPV1 | |
| SCHEMBL4788004 | 0.89 | TRPV1 (0.51) | TRPV1CYP2D6 | |
| SCHEMBL4350468 | 0.89 | TRPV1 (0.65) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL4787861 | 0.89 | TRPV1 (0.52) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL4786870 | 0.88 | TRPV1 (0.52) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL4785062 | 0.87 | TRPV1 (0.49) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL4786173 | 0.87 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL4350187 | 0.87 | TRPV1 (0.64) | TRPV1CYP3A4CYP2D6 | |
| SCHEMBL3321372 | 0.87 | TRPV1 (0.74) | TRPV1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110863-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-09-18 | — | — | WO | disclosed |