Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789546 | 1.00 | MAP2K1 (0.82) | MAP2K1MAP2K2 | |
| SCHEMBL4789695 | 1.00 | MAP2K1 (0.82) | MAP2K1MAP2K2 | |
| SCHEMBL4789526 | 0.90 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL4789157 | 0.90 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL4789161 | 0.90 | MAP2K1 (1.00) | MAP2K1 | |
| SCHEMBL5063523 | 0.89 | MAP2K1 (0.81) | MAP2K1MAP2K2 | |
| SCHEMBL4789815 | 0.88 | MAP2K1 (0.64) | MAP2K1MAP2K2 | |
| SCHEMBL4789158 | 0.85 | MAP2K1 (0.91) | MAP2K1 | |
| SCHEMBL4789154 | 0.85 | MAP2K1 (0.91) | MAP2K1 | |
| SCHEMBL5058419 | 0.82 | MAP2K1 (1.00) | MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312307-A1 | MAPK/ERK KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | claimed |
| WO-2008148034-A1 | MAPK/ERK KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-04 | — | — | WO | claimed |
| US-20080312307-A1 | MAPK/ERK KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| WO-2008148034-A1 | MAPK/ERK KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312307-A1 | MAPK/ERK KINASE INHIBITORS | MAPK1, MAP3K1, MAP3K7 | MAP2K1 45/4885MAP2K2 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.