⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599544 | 1.00 | — | — | |
| SCHEMBL19853007 | 1.00 | — | — | |
| SCHEMBL19853014 | 1.00 | — | — | |
| SCHEMBL1931507 | 1.00 | — | — | |
| SCHEMBL19853037 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL22491838 | 0.98 | CYP2D6 (0.56) | — | |
| SCHEMBL24690879 | 0.81 | — | — | |
| SCHEMBL21768270 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL1318333 | 0.79 | SLC1A2 (0.45) | — | |
| SCHEMBL21768278 | 0.79 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039335-A2 | POLYMER COMPOSITIONS COMPRISING ANTIFIBROTIC AGENTS, AND METHODS OF TREATMENT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARATION THEREFOR | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2004-05-13 | — | — | WO | claimed |
| US-20210276954-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-09-09 | — | — | US | disclosed |
| WO-2018025295-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2018-02-08 | — | — | WO | disclosed |
| WO-2016053794-A1 | QUINAZOLINE-BASED KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-04-07 | — | — | WO | disclosed |
| WO-2008157537-A2 | COMPOSITIONS AND METHODS OF USE FOR TREATING OR PREVENTING LIPID RELATED DISORDERS | IRONWOOD PHARMACEUTICALS, INC (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-1828384-A1 | MUTANT OF THE PROB GENE FROM CORYNEFORM BACTERIA | Degussa GmbH (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2007062316-A2 | TRANS-3,5-DISUBSTITUTEDPYRROLIDINE: ORGANOCATALYST FOR ANTI-MANNICH REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2006066758-A1 | MUTANT OF THE PROB GENE FROM CORYNEFORM BACTERIA | DEGUSSA GMBH (DE) | 2006-06-29 | — | — | WO | disclosed |
| EP-1017358-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015136-A1 | REDUCTION OF HAIR GROWTH | THE GILLETTE COMPANY (US) | 1999-04-01 | — | — | WO | disclosed |