Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118406 | 1.00 | PTGER4 (0.43) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL4105625 | 0.93 | PTGER4 (0.43) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL4125204 | 0.90 | PTGER4 (0.52) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL4107654 | 0.90 | PTGER4 (0.52) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL4794136 | 0.90 | PTGER4 (0.52) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL4112956 | 0.88 | PTGER4 (0.46) | PTGER4PTGER2PTGER1PTGER3 | |
| SCHEMBL4127088 | 0.84 | PTGER4 (0.41) | PTGER4PTGER2 | |
| SCHEMBL4127094 | 0.84 | PTGER4 (0.41) | PTGER4PTGER2 | |
| SCHEMBL4791155 | 0.84 | PTGER4 (0.41) | PTGER4PTGER2 | |
| SCHEMBL4112697 | 0.81 | PTGER4 (0.52) | PTGER4PTGER2PTGER1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912977-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | Merck Frosst Canada Ltd. (CA) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007014454-A1 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | MERCK FROSST CANADA LTD. (CA) | 2007-02-08 | — | — | WO | disclosed |