Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.68 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881905 | 1.00 | HRH3 (0.68) | HRH3L3MBTL3L3MBTL1BCHECNR1 | |
| SCHEMBL2884371 | 0.90 | HRH3 (0.71) | HRH3L3MBTL3L3MBTL1CNR2 | |
| SCHEMBL2878753 | 0.90 | HRH3 (0.71) | HRH3L3MBTL3L3MBTL1CNR2 | |
| Hydrochloric Acid SCHEMBL2885717 | 0.89 | HRH3 (0.70) | HRH3L3MBTL3L3MBTL1CNR2 | |
| SCHEMBL2884880 | 0.89 | HRH3 (0.69) | HRH3L3MBTL3L3MBTL1BCHECNR1 | |
| SCHEMBL2886056 | 0.88 | HRH3 (0.67) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL2879262 | 0.88 | HRH3 (0.67) | HRH3L3MBTL3L3MBTL1CNR2 | |
| SCHEMBL2884311 | 0.88 | HRH3 (0.65) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL2884415 | 0.87 | HRH3 (0.67) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL2886669 | 0.87 | HRH3 (0.67) | HRH3L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994022-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2008-11-26 | — | — | EP | claimed |
| WO-2007108936-A2 | N-SUBSTITUTED-AZACYCLYLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-09-27 | — | — | WO | claimed |