Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 20/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091313 | 0.87 | PTGER1 (0.85) | PTGER1CYP1A2 | |
| SCHEMBL4085693 | 0.86 | PTGER1 (0.83) | PTGER1 | |
| SCHEMBL4091254 | 0.86 | PTGER1 (0.83) | PTGER1 | |
| SCHEMBL4090827 | 0.86 | PTGER1 (0.79) | PTGER1CYP1A2 | |
| SCHEMBL4085523 | 0.85 | PTGER1 (1.00) | PTGER1 | |
| SCHEMBL4093184 | 0.84 | PTGER1 (1.00) | PTGER1 | |
| SCHEMBL252356 | 0.84 | PTGER1 (0.79) | PTGER1 | |
| SCHEMBL4085873 | 0.84 | PTGER1 (0.85) | PTGER1 | |
| SCHEMBL4092092 | 0.84 | PTGER1 (1.00) | PTGER1 | |
| SCHEMBL4097555 | 0.83 | PTGER1 (1.00) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874303-A1 | PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS | GLAXO GROUP LIMITED (GB) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114313-A1 | PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS | GLAXO GROUP LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |