Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081023 | 0.72 | KDM4E (0.52) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL982700 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7623213 | 0.69 | MAPT (0.38) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL376865 | 0.68 | PPARA (0.39) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2834876 | 0.67 | ESR1 (0.53) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7171403 | 0.67 | HSP90AA1 (0.44) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7774725 | 0.67 | KDM4E (0.68) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6080005 | 0.67 | MAPT (0.48) | MAPTMEN1KMT2AL3MBTL1TDP1 | |
| Naphthalene SCHEMBL1132213 | 0.66 | HSD17B10 (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27913538 | 0.66 | KDM4E (0.49) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922299-A1 | METHOD FOR PRODUCING ORGANOMETALLIC FRAMEWORK MATERIALS CONTAINING MAIN GROUP METAL IONS | BASF SE (DE) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007023134-A1 | METHOD FOR PRODUCING ORGANOMETALLIC FRAMEWORK MATERIALS CONTAINING MAIN GROUP METAL IONS | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-01 | — | — | WO | disclosed |