Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 19/20 | 0.81 |
| ▸ | PGR | P06401 | 8/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.81 |
| ▸ | AR | P10275 | 1/20 | 0.79 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287184 | 0.91 | NR3C2 (0.77) | NR3C2PGRNR3C1ARSLC5A1 | |
| SCHEMBL4291579 | 0.90 | NR3C2 (1.00) | NR3C2PGRNR3C1AR | |
| SCHEMBL4295689 | 0.89 | NR3C2 (1.00) | NR3C2PGRNR3C1AR | |
| SCHEMBL4291050 | 0.88 | NR3C2 (0.81) | NR3C2PGRNR3C1AR | |
| SCHEMBL4288530 | 0.88 | NR3C2 (1.00) | NR3C2PGRNR3C1AR | |
| SCHEMBL4297574 | 0.87 | NR3C2 (0.85) | NR3C2PGRNR3C1AR | |
| SCHEMBL4300312 | 0.86 | NR3C2 (0.82) | NR3C2PGRNR3C1AR | |
| SCHEMBL4290689 | 0.84 | NR3C2 (0.88) | NR3C2PGRNR3C1AR | |
| SCHEMBL4293879 | 0.83 | NR3C2 (0.78) | NR3C2PGRNR3C1AR | |
| SCHEMBL4292036 | 0.83 | NR3C2 (1.00) | NR3C2PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971596-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | Takeda Pharmaceutical Company Limited (JP) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007077961-A2 | FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-12 | — | — | WO | disclosed |