Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664486 | 0.88 | S1PR5 (0.56) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL4662867 | 0.84 | S1PR5 (0.55) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL4664574 | 0.79 | S1PR1 (0.47) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL4666332 | 0.77 | S1PR1 (0.48) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16493532 | 0.76 | S1PR1 (0.45) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL2939694 | 0.75 | S1PR5 (0.48) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL13271331 | 0.74 | S1PR5 (0.58) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL16493516 | 0.73 | S1PR1 (0.44) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL4792492 | 0.73 | S1PR1 (0.40) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL4663091 | 0.72 | S1PR5 (0.53) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638551-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-12-31 | — | — | EP | disclosed |
| EP-1638551-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004103309-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |