Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793241 | 0.93 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL14547563 | 0.92 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL4795396 | 0.91 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4795063 | 0.90 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL14547631 | 0.89 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL4794221 | 0.88 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL14547560 | 0.88 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL4794153 | 0.85 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL4792690 | 0.84 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL4794262 | 0.83 | PPARD (0.49) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937647-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | Inpharmatica Limited (GB) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007036727-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007036727-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |