Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051367 | 0.87 | EGFR (0.47) | CNR2CNR1EGFRCDK1CYP1A2 | |
| SCHEMBL4791081 | 0.86 | MAPT (0.54) | CNR2CNR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14051372 | 0.86 | CNR2 (0.61) | CNR2CNR1CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL4873070 | 0.85 | CNR2 (0.61) | CNR2CNR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14051213 | 0.85 | CNR2 (0.61) | CNR2CNR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14051369 | 0.84 | SRC (0.41) | MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL14051127 | 0.84 | CNR2 (0.59) | CNR2CNR1CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL4868903 | 0.84 | CNR2 (0.60) | CNR2CNR1CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL4793174 | 0.83 | SRC (0.41) | MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL4793635 | 0.83 | CNR2 (0.74) | CNR2CNR1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
| US-20080221097-A1 | Imidazopyridine Derivatives as Cannabinoid Receptor Ligands | GLAXO GROUP LIMITED | 2008-09-11 | — | — | US | disclosed |
| US-20080221097-A1 | Imidazopyridine Derivatives as Cannabinoid Receptor Ligands | GLAXO GROUP LIMITED | 2008-09-11 | — | — | US | disclosed |
| US-20080221097-A1 | Imidazopyridine Derivatives as Cannabinoid Receptor Ligands | GLAXO GROUP LIMITED | 2008-09-11 | — | — | US | disclosed |
| EP-1912985-A1 | IMIDAZOPYRIDINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017237-A1 | IMIDAZOPYRIDINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007017237-A1 | IMIDAZOPYRIDINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221097-A1 | Imidazopyridine Derivatives as Cannabinoid Receptor Ligands | CNR1, CNR2, TRPV1 | CNR2 2/4885CNR1 1/4885CYP3A4 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.