Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791948 | 0.89 | TLR7 (0.32) | TLR7TLR8 | |
| SCHEMBL4791828 | 0.88 | TLR7 (0.32) | TLR7TLR8 | |
| SCHEMBL4795504 | 0.87 | TLR7 (0.32) | TLR7TLR8GAATDP1 | |
| SCHEMBL5341182 | 0.81 | EPHX1 (0.37) | GAATDP1 | |
| SCHEMBL4794141 | 0.75 | BRD4 (0.30) | TLR7 | |
| SCHEMBL5335479 | 0.75 | EPHX1 (0.37) | GAATDP1 | |
| SCHEMBL4792688 | 0.74 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6847185 | 0.74 | TLR8 (0.52) | TLR7TLR8 | |
| SCHEMBL4794536 | 0.73 | TLR7 (0.43) | TLR7TLR8GAA | |
| SCHEMBL4882082 | 0.72 | EPHX1 (0.39) | GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |