Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1265783 | 0.79 | MAP3K14 (0.51) | MAP3K14ADRA2AHCRTR2TAAR1TERT | |
| SCHEMBL27859985 | 0.79 | MAP3K14 (0.51) | MAP3K14ADRA2AHCRTR2TAAR1TERT | |
| SCHEMBL21436437 | 0.79 | MAP3K14 (0.51) | MAP3K14ADRA2AHCRTR2TAAR1TERT | |
| SCHEMBL24997240 | 0.79 | MAP3K14 (0.75) | MAP3K14ADRA2AHCRTR2TERTDRD2 | |
| SCHEMBL13198495 | 0.79 | MAP3K14 (0.51) | MAP3K14ADRA2AHCRTR2TERTDRD2 | |
| SCHEMBL24075122 | 0.79 | MAP3K14 (0.51) | MAP3K14ADRA2AHCRTR2TERTDRD2 | |
| SCHEMBL16397491 | 0.79 | MAP3K14 (0.75) | MAP3K14ADRA2AHCRTR2TERTDRD2 | |
| SCHEMBL24393413 | 0.79 | MAP3K14 (0.75) | MAP3K14ADRA2AHCRTR2TERTDRD2 | |
| SCHEMBL8912565 | 0.79 | MAP3K14 (0.51) | MAP3K14ADRA2AHCRTR2TAAR1TERT | |
| Hydrochloric Acid SCHEMBL1066095 | 0.77 | MAP3K14 (0.50) | MAP3K14ADRA2AHCRTR2TAAR1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874772-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108103-A1 | PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION | PHARMACOPEIA, INC. (US) | 2006-10-12 | — | — | WO | disclosed |