SCHEMBL4794635

SCHEMBL4794635

CCc1c(C(=O)NC2CCCCC2)nn(-c2ccccc2Cl)c1-c1ccc(OS(=O)(=O)CCC(F)(F)F)cc1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.56
CNR2 P34972 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4911429 0.93 CNR1 (0.57) CNR1CNR2
SCHEMBL4612291 0.91 CNR1 (0.59) CNR1CNR2
SCHEMBL4907896 0.85 CNR1 (0.68) CNR1CNR2
SCHEMBL4906459 0.84 CNR1 (0.59) CNR1CNR2
SCHEMBL4910449 0.84 CNR1 (0.53) CNR1CNR2
SCHEMBL4907354 0.84 CNR1 (0.53) CNR1CNR2
SCHEMBL4599751 0.83 CNR1 (0.57) CNR1CNR2
SCHEMBL4891882 0.82 CNR1 (0.57) CNR1CNR2
SCHEMBL4885390 0.82 CNR1 (0.57) CNR1CNR2
SCHEMBL4894758 0.82 CNR1 (0.57) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1910331-A1 PYRAZOLE DERIVATIVES AS CBl MODULATORS AstraZeneca AB (SE) 2008-04-16 EP disclosed
WO-2007010217-A1 PYRAZOLE DERIVATIVES AS CBl MODULATORS ASTRAZENECA AB (SE) 2007-01-25 WO disclosed