Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479470 | 1.00 | RXFP1 (0.49) | RXFP1MEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL479469 | 1.00 | RXFP1 (0.49) | RXFP1MEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL479586 | 0.93 | MAPT (0.53) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL479582 | 0.93 | MAPT (0.53) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL479584 | 0.93 | MAPT (0.53) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL481166 | 0.92 | RXFP1 (0.51) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL481167 | 0.92 | RXFP1 (0.51) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2569219 | 0.91 | RXFP1 (0.51) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3159875 | 0.91 | RXFP1 (0.51) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2572320 | 0.91 | RXFP1 (0.51) | RXFP1MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |