Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086306 | 0.82 | AR (0.55) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL4078988 | 0.78 | GAA (0.55) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL4076521 | 0.78 | KMT2A (0.57) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL3530239 | 0.77 | KMT2A (0.56) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL4081973 | 0.76 | AR (0.51) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL3161083 | 0.73 | GAA (0.49) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL4084526 | 0.73 | AR (0.53) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL3526486 | 0.73 | GAA (0.49) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL3170904 | 0.73 | KMT2A (0.52) | ARGAAKMT2AMEN1MAPT | |
| SCHEMBL4078584 | 0.71 | AR (0.51) | ARGAAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021309-A1 | IMIDAZOLIDIN-2-ONE DERIVATIVES USEFUL AS PR MODULATORS | WYETH (US) | 2008-02-21 | — | — | WO | disclosed |