Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795387 | 1.00 | HSD17B3 (0.59) | HSD17B3CYP11B2 | |
| SCHEMBL4799369 | 0.89 | HSD17B3 (0.62) | HSD17B3 | |
| SCHEMBL4799378 | 0.89 | HSD17B3 (0.62) | HSD17B3 | |
| SCHEMBL4798256 | 0.89 | HSD17B3 (0.61) | HSD17B3 | |
| SCHEMBL4798271 | 0.89 | HSD17B3 (0.61) | HSD17B3 | |
| SCHEMBL4800979 | 0.88 | HSD17B3 (0.60) | HSD17B3 | |
| SCHEMBL4800993 | 0.88 | HSD17B3 (0.60) | HSD17B3 | |
| SCHEMBL15088532 | 0.87 | HSD17B3 (0.52) | HSD17B3CYP11B2 | |
| SCHEMBL4800262 | 0.83 | HSD17B3 (0.67) | HSD17B3 | |
| SCHEMBL4800268 | 0.83 | HSD17B3 (0.67) | HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417040-B2 | Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-26 | — | — | US | disclosed |