Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4794813 | 0.90 | PPARD (0.41) | PPARDPPARAPPARGRARGRORC | |
| SCHEMBL4794221 | 0.88 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL4792787 | 0.87 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL4792690 | 0.84 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL14547631 | 0.84 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL4957155 | 0.81 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL14547559 | 0.80 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL4792986 | 0.79 | TEAD1 (0.49) | PPARDPPARAPPARG | |
| SCHEMBL4795396 | 0.79 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4792218 | 0.78 | PPARD (0.56) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937647-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | Inpharmatica Limited (GB) | 2008-07-02 | — | — | EP | claimed |
| WO-2007036727-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | claimed |
| EP-1937647-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | Inpharmatica Limited (GB) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007036727-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007036727-A1 | CONDENSED PYRAZOLE DERIVATIVES AS PPAR AGONISTS II | INPHARMATICA LIMITED (GB) | 2007-04-05 | — | — | WO | disclosed |