Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393688 | 0.94 | HSD17B3 (1.00) | HSD17B3 | |
| SCHEMBL4801126 | 0.90 | HSD17B3 (0.92) | HSD17B3 | |
| Trifluoroacetic Acid SCHEMBL4803128 | 0.85 | HSD17B3 (0.75) | HSD17B3 | |
| SCHEMBL4803100 | 0.85 | HSD17B3 (1.00) | HSD17B3 | |
| Trifluoroacetic Acid SCHEMBL4803186 | 0.85 | HSD17B3 (0.87) | HSD17B3 | |
| SCHEMBL4798240 | 0.83 | HSD17B3 (0.79) | HSD17B3 | |
| SCHEMBL4799858 | 0.82 | HSD17B3 (0.80) | HSD17B3 | |
| Trifluoroacetic Acid SCHEMBL4798233 | 0.81 | HSD17B3 (0.69) | HSD17B3 | |
| Trifluoroacetic Acid SCHEMBL4802517 | 0.81 | HSD17B3 (0.81) | HSD17B3 | |
| Trifluoroacetic Acid SCHEMBL4801457 | 0.80 | HSD17B3 (0.67) | HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417040-B2 | Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-26 | — | — | US | disclosed |