Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | XIAP | P98170 | 1/20 | 0.57 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.52 |
| ▸ | CPA3 | P15088 | 3/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795710 | 1.00 | ALPI (0.57) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL434525 | 0.86 | ALPI (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL434524 | 0.86 | ALPI (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27626196 | 0.86 | ALPI (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL9177995 | 0.86 | ALPI (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27878042 | 0.85 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27878043 | 0.85 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2781695 | 0.82 | ALPI (0.50) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL22078519 | 0.82 | ALPI (0.55) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL2780442 | 0.82 | ALPI (0.50) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112494656-B | Insulin receptor partial agonists | 默沙东有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-112494656-A | Partial insulin receptor agonists | 默沙东公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-105324397-B | Insulin-incretin conjugates | 印第安纳大学研究及科技有限公司 | 2020-01-14 | — | — | CN | disclosed |
| CN-105792852-B | Glucose-responsive insulin conjugates | 默沙东公司 | 2019-12-10 | — | — | CN | disclosed |
| WO-2008004529-A1 | NOVEL FLUORESCENT AMINO ACID DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2008-01-10 | — | — | WO | disclosed |
| EP-0658585-B1 | Aminophenylalanine derivatives, process for their production, their use and agents containing them as anti-coagulants | STUEBER WERNER (DE) | 2000-07-19 | — | — | EP | disclosed |
| EP-0658585-A3 | Aminophenylalanine derivatives, process for their production, their use and agents containing them as anti-coagulants. | BEHRINGWERKE AG (DE) | 1995-10-18 | — | — | EP | disclosed |
| EP-0658585-A2 | Aminophenylalanine derivatives, process for their production, their use and agents containing them as anti-coagulants | BEHRINGWERKE Aktiengesellschaft (DE) | 1995-06-21 | — | — | EP | disclosed |