Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.75 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303120 | 0.88 | CHRNA7 (0.67) | CHRNA7MMP2NPC1 | |
| SCHEMBL6311908 | 0.88 | CHRNA7 (0.67) | CHRNA7CTSLCTSBCTSKMEN1 | |
| SCHEMBL6311905 | 0.88 | CHRNA7 (0.67) | CHRNA7CTSLCTSBCTSKMEN1 | |
| SCHEMBL6305799 | 0.88 | CHRNA7 (0.67) | CHRNA7MEN1KMT2APOLB | |
| SCHEMBL6303119 | 0.88 | CHRNA7 (0.67) | CHRNA7MMP2NPC1 | |
| SCHEMBL6305792 | 0.88 | CHRNA7 (0.67) | CHRNA7MEN1KMT2APOLB | |
| SCHEMBL5917831 | 0.86 | CHRNA7 (1.00) | CHRNA7MEN1KMT2AMMP2NPC1 | |
| SCHEMBL5917833 | 0.86 | CHRNA7 (1.00) | CHRNA7MEN1KMT2AMMP2NPC1 | |
| SCHEMBL6283023 | 0.86 | CHRNA7 (1.00) | CHRNA7MEN1KMT2AMMP2NPC1 | |
| SCHEMBL6309604 | 0.85 | NPC1 (0.67) | CHRNA7KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |