Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 19/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891753 | 0.90 | P2RY12 (0.82) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL3217388 | 0.89 | P2RY12 (0.82) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL3589485 | 0.84 | P2RY12 (0.70) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL3226299 | 0.83 | P2RY12 (0.80) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4873260 | 0.83 | P2RY12 (0.85) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL3327629 | 0.83 | P2RY12 (0.84) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4783399 | 0.82 | P2RY12 (0.83) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL3325916 | 0.82 | P2RY12 (0.82) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL3590558 | 0.82 | P2RY12 (0.82) | P2RY12CYP3A4CYP2C9CHRM2DRD3 | |
| SCHEMBL4740602 | 0.82 | P2RY12 (0.71) | P2RY12CYP3A4CYP2C9CHRM2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085119-A1 | NEW PYRIDINE ANALOGUES VIII 518 | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |