Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730326 | 0.87 | QPCT (0.60) | POLBBLMTDP1KCNJ1MAPT | |
| SCHEMBL9518785 | 0.85 | KCNJ1 (0.66) | POLBBLMTDP1KCNJ1MAPT | |
| SCHEMBL18530872 | 0.79 | MAPT (0.56) | POLBBLMTDP1KCNJ1MAPT | |
| SCHEMBL3328195 | 0.79 | KCNJ1 (0.71) | POLBBLMTDP1KCNJ1MAPT | |
| SCHEMBL1449005 | 0.79 | MAPT (0.63) | POLBBLMTDP1KCNJ1MAPT | |
| SCHEMBL11768462 | 0.79 | NOTUM (0.58) | POLBBLMTDP1KCNJ1MAPT | |
| SCHEMBL9969614 | 0.79 | NOTUM (0.54) | POLBBLMTDP1NOTUM | |
| SCHEMBL12615985 | 0.78 | NOTUM (0.78) | POLBBLMTDP1KCNJ1MAPT | |
| SCHEMBL2731943 | 0.77 | KCNH2 (0.63) | KCNJ1ALDH1A1HPGDKCNH2 | |
| SCHEMBL2732692 | 0.77 | KCNH2 (0.63) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016811-A2 | AMINOPIPERIDINES AND REALTED COMPOUNDS | NEUROGEN CORPORATION (US) | 2008-02-07 | — | — | WO | disclosed |