Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.60 |
| ▸ | CCR6 | P51684 | 2/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797610 | 1.00 | MEN1 (0.68) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL14252589 | 1.00 | MEN1 (0.68) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL12934213 | 0.89 | MEN1 (0.68) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL2084941 | 0.88 | MEN1 (0.85) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL2084943 | 0.88 | MEN1 (0.85) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL13586997 | 0.85 | KAT2B (0.65) | MEN1KMT2APOLBCTDSP1DUSP3 | |
| SCHEMBL4551870 | 0.84 | PIM1 (0.63) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL4551871 | 0.84 | PIM1 (0.63) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL4551869 | 0.84 | PIM1 (0.63) | MEN1KMT2APOLBTDP1CTDSP1 | |
| SCHEMBL12934212 | 0.77 | MEN1 (0.53) | MEN1KMT2APOLBCTDSP1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | claimed |
| US-7344850-B2 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | PRINCETON UNIVERSITY (US) | 2008-03-18 | — | — | US | disclosed |
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | disclosed |