Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14202739 | 0.97 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL14201931 | 0.90 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL14204203 | 0.89 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL4731496 | 0.86 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL14204730 | 0.85 | MAPK14 (0.53) | MAPK14 | |
| SCHEMBL14202908 | 0.85 | MAPK14 (0.49) | MAPK14 | |
| SCHEMBL4798639 | 0.85 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL4730691 | 0.81 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL14203884 | 0.81 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL4731642 | 0.80 | MAPK14 (0.54) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053158-A1 | INHIBITORS OF P38 MITOGEN-ACTIVATED PROTEIN KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008053158-A1 | INHIBITORS OF P38 MITOGEN-ACTIVATED PROTEIN KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |