Styrene

Styrene

SCHEMBL4798421

C=CC(=O)OCCCC.C=Cc1ccccc1.C[C](C)C

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.63
HPGD P15428 1/20 0.63
THRB P10828 5/20 0.50
TDP1 Q9NUW8 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 3/20 0.46
ATM Q13315 1/20 0.45
HCAR2 Q8TDS4 1/20 0.44
THRA P10827 1/20 0.43
APP P05067 1/20 0.43
MAPK1 P28482 2/20 0.43
TP53 P04637 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HSD17B10 Q99714 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL67823 0.97 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3196230 0.97 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3696057 0.97 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL28887747 0.97 TSHR (0.67) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL28616597 0.94 TSHR (0.59) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL28311085 0.94 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL1010365 0.94 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL3111143 0.94 TSHR (0.63) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL1563744 0.93 TSHR (0.58) TSHRHPGDTHRBTDP1L3MBTL1
Styrene SCHEMBL28684767 0.93 TSHR (0.61) TSHRHPGDTHRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462445-B2 Image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-12-09 US disclosed
US-7445884-B2 Photothermographic material, development method and thermal development device thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-04 US disclosed
US-7364841-B2 Comprising support having thereon light-insensitive organic silver salt grains, photosensitive silver halide grains, a reducing agent for silver ions and a binder; improved storage stability, image lasting quality; use in medical diagnosis and graphic arts KONICA MINOLTA & MEDICAL GRAPHIC, INC. (JP) 2008-04-29 US disclosed
US-20080057447-A1 rapid thermal processing of a photothermographic materials; involving a transport feed roller, light-insensitive layer or back coating layer contains a lubricant fatty ester, a biphenol derivatives reducing agent for silver KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-03-06 US disclosed
US-7326527-B2 Silver salt photothermographic dry imaging material and image forming method by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC (JP) 2008-02-05 US disclosed
US-7309565-B2 Process for treating photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-18 US disclosed
US-7270945-B2 Image forming method using photothermographic material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-18 US disclosed
US-7229752-B2 Nonaqueous dispersion of particles insoluble in solvent; mixture containing metal complex as dopant KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-06-12 US disclosed
US-7229751-B2 Silver salt photothermographic dry imaging material and image forming method using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-06-12 US disclosed
US-20070105059-A1 IMAGE FORMING METHOD USING PHOTOTHERMOGRAPHIC MATERIAL KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-05-10 US disclosed
US-20060046209-A1 Image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2006-03-02 US disclosed
US-20060029892-A1 Nonaqueous dispersion of particles insoluble in solvent; mixture containing metal complex as dopant KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2006-02-09 US disclosed
US-20060003272-A1 Photothermographic material, development method and thermal development device thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-01-05 US disclosed
US-20050271986-A1 Process for treating photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-12-08 US disclosed
US-20050250057-A1 Image forming method using photothermographic material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-11-10 US disclosed
US-20050158676-A1 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-07-21 US disclosed
US-20050136366-A1 Silver salt photothermographic dry imaging material and image forming method using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-06-23 US disclosed
US-20050112514-A1 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-05-26 US disclosed
US-20050089807-A1 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-04-28 US disclosed
US-20050064352-A1 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-03-24 US disclosed