Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.80 |
| ▸ | RAB9A | P51151 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | APEX1 | P27695 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | EP300 | Q09472 | 2/20 | 0.71 |
| ▸ | XPA | P23025 | 7/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.63 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4798498 | 1.00 | MEN1 (0.80) | MEN1KMT2ARAB9APOLBKDM4E | |
| SCHEMBL19652479 | 0.88 | MEN1 (0.88) | MEN1KMT2ARAB9APOLBKDM4E | |
| SCHEMBL19652471 | 0.86 | MEN1 (0.74) | MEN1KMT2ARAB9APOLBKDM4E | |
| SCHEMBL19653404 | 0.85 | EP300 (0.88) | MEN1KMT2ARAB9APOLBKDM4E | |
| SCHEMBL19654118 | 0.83 | MEN1 (0.73) | MEN1KMT2ARAB9APOLBKDM4E | |
| SCHEMBL12810379 | 0.83 | MEN1 (0.77) | MEN1KMT2ARAB9AMAPTTDP1 | |
| SCHEMBL19652470 | 0.82 | XPA (1.00) | MEN1KMT2ARAB9APOLBKDM4E | |
| SCHEMBL20840289 | 0.82 | MEN1 (0.90) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL20840288 | 0.82 | MEN1 (0.90) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL26459231 | 0.81 | MEN1 (0.69) | MEN1KMT2ARAB9APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | claimed |
| US-7344850-B2 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | PRINCETON UNIVERSITY (US) | 2008-03-18 | — | — | US | disclosed |
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | disclosed |