Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 18/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 18/20 | 1.00 |
| ▸ | POLB | P06746 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.90 |
| ▸ | RAB9A | P51151 | 3/20 | 0.90 |
| ▸ | GAA | P10253 | 2/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.83 |
| ▸ | PKM | P14618 | 1/20 | 0.80 |
| ▸ | CTDSP1 | Q9GZU7 | 5/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.70 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.70 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.70 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.70 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12008841 | 1.00 | MEN1 (1.00) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL4799078 | 1.00 | MEN1 (1.00) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12009006 | 0.95 | KMT2A (1.00) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12008834 | 0.90 | KMT2A (1.00) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12008948 | 0.89 | MEN1 (0.85) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12008994 | 0.89 | MEN1 (1.00) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12008929 | 0.88 | MEN1 (0.81) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12008985 | 0.88 | MEN1 (0.81) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12008951 | 0.88 | MEN1 (0.81) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL12008572 | 0.88 | KMT2A (0.89) | MEN1KMT2APOLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | claimed |
| US-7344850-B2 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | PRINCETON UNIVERSITY (US) | 2008-03-18 | — | — | US | disclosed |
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | disclosed |