Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390007 | 0.93 | HSD17B3 (0.70) | HSD17B3NOTUM | |
| Trifluoroacetic Acid SCHEMBL4797354 | 0.87 | HSD17B3 (0.66) | HSD17B3NOTUM | |
| Trifluoroacetic Acid SCHEMBL4798233 | 0.85 | HSD17B3 (0.69) | HSD17B3NOTUM | |
| Trifluoroacetic Acid SCHEMBL4800399 | 0.83 | HSD17B3 (0.72) | HSD17B3NOTUM | |
| SCHEMBL4795163 | 0.83 | HSD17B3 (0.91) | HSD17B3NOTUM | |
| SCHEMBL4802501 | 0.82 | HSD17B3 (0.73) | HSD17B3NOTUM | |
| Trifluoroacetic Acid SCHEMBL4801509 | 0.82 | HSD17B3 (0.64) | HSD17B3 | |
| Trifluoroacetic Acid SCHEMBL4803128 | 0.82 | HSD17B3 (0.75) | HSD17B3NOTUM | |
| Trifluoroacetic Acid SCHEMBL4802517 | 0.81 | HSD17B3 (0.81) | HSD17B3NOTUM | |
| SCHEMBL4800410 | 0.81 | HSD17B3 (0.75) | HSD17B3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417040-B2 | Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-26 | — | — | US | disclosed |