Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801400 | 0.96 | HSD17B3 (0.93) | HSD17B3 | |
| SCHEMBL4800392 | 0.89 | HSD17B3 (0.80) | HSD17B3 | |
| SCHEMBL4801965 | 0.87 | HSD17B3 (0.77) | HSD17B3 | |
| SCHEMBL4799597 | 0.85 | HSD17B3 (0.74) | HSD17B3 | |
| SCHEMBL4797955 | 0.84 | HSD17B3 (1.00) | HSD17B3 | |
| SCHEMBL4798035 | 0.83 | HSD17B3 (0.71) | HSD17B3 | |
| SCHEMBL4798993 | 0.82 | HSD17B3 (1.00) | HSD17B3 | |
| SCHEMBL4798041 | 0.81 | HSD17B3 (0.76) | HSD17B3 | |
| SCHEMBL4799239 | 0.81 | HSD17B3 (0.86) | HSD17B3 | |
| SCHEMBL4800947 | 0.80 | HSD17B3 (0.92) | HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417040-B2 | Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-08-26 | — | — | US | disclosed |