Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075581 | 0.87 | TSHR (0.58) | TSHRFAAHLMNAEPHX2MAPT | |
| Allyl Hexanoate SCHEMBL1869217 | 0.85 | TSHR (0.96) | TSHRFAAHDGKALMNAMAPT | |
| Allyl Hexanoate SCHEMBL21086 | 0.85 | TSHR (0.96) | TSHRFAAHDGKALMNAMAPT | |
| SCHEMBL19133353 | 0.84 | TSHR (1.00) | TSHRFAAHDGKALMNAMAPT | |
| SCHEMBL3503097 | 0.84 | TSHR (1.00) | TSHRFAAHDGKALMNAMAPT | |
| Allyl Heptanoate SCHEMBL4147097 | 0.84 | TSHR (1.00) | TSHRFAAHDGKALMNAMAPT | |
| Allyl Heptanoate SCHEMBL20820 | 0.84 | TSHR (1.00) | TSHRFAAHDGKALMNAMAPT | |
| SCHEMBL1176823 | 0.84 | TSHR (1.00) | TSHRFAAHDGKALMNAMAPT | |
| SCHEMBL440501 | 0.84 | TSHR (1.00) | TSHRFAAHDGKALMNAMAPT | |
| SCHEMBL439396 | 0.84 | TSHR (1.00) | TSHRFAAHDGKALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074858-A1 | INTERMEDIATES AND PROCESS FOR THE PRODUCTION OF 5-SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2008-06-26 | — | — | WO | disclosed |