⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191168 | 0.72 | — | — | |
| SCHEMBL2486612 | 0.69 | — | — | |
| SCHEMBL315661 | 0.69 | — | — | |
| SCHEMBL3879113 | 0.67 | — | — | |
| SCHEMBL14933116 | 0.67 | — | — | |
| Water SCHEMBL2152723 | 0.67 | — | — | |
| SCHEMBL9733633 | 0.67 | — | — | |
| SCHEMBL13621673 | 0.67 | — | — | |
| SCHEMBL588539 | 0.67 | — | — | |
| SCHEMBL4264961 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630958-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2017-04-25 | — | — | US | claimed |
| US-20150197515-A1 | NOVEL TRIAZINE COMPOUNDS | SPHAERA PHARMA PTE. LTD. (SG) | 2015-07-16 | — | — | US | claimed |
| WO-2014016849-A9 | NOVEL TRIAZINE COMPOUNDS | SPHAERA PHARMA PTE. LTD. (SG) | 2014-03-13 | — | — | WO | claimed |
| JP-56010175-A | — | — | None | — | — | JP | disclosed |
| EP-2874632-B1 | TRIAZINE COMPOUND HAVING PI3K-ALPHA AND MTOR INHIBITING ACTIVITY | SPHAERA PHARMA PTE LTD (SG) | 2020-06-17 | — | — | EP | disclosed |
| EP-2874632-B1 | TRIAZINE COMPOUND HAVING PI3K-ALPHA AND MTOR INHIBITING ACTIVITY | SPHAERA PHARMA PTE LTD (SG) | 2020-06-17 | — | — | EP | disclosed |
| US-9765030-B2 | Benzylamine derivatives and their utility as cholesterol ester-transfer protein inhibitors | DR. REDDY'S LABORATORIES LTD. (IN) | 2017-09-19 | — | — | US | disclosed |
| US-9630958-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2017-04-25 | — | — | US | disclosed |
| US-9630958-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2017-04-25 | — | — | US | disclosed |
| EP-1981342-B1 | SELECTIVE BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS | REDDYS LAB LTD DR (IN) | 2016-11-30 | — | — | EP | disclosed |
| US-20150197515-A1 | NOVEL TRIAZINE COMPOUNDS | SPHAERA PHARMA PTE. LTD. (SG) | 2015-07-16 | — | — | US | disclosed |
| WO-2001025220-A1 | TRIAZINE KINASE INHIBITORS | AMGEN INC. (US) | 2001-04-12 | — | — | WO | disclosed |
| US-5962452-A | SUNSCREEN AGENTS, DRUGS, COSMETICS, VETERINARY MEDICINE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-05 | — | — | US | disclosed |
| US-5955060-A | COSMETICS AND VETERINARY MEDICINE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0878469-A1 | Resorcinyl-triazines | Ciba SC Holding AG (CH) | 1998-11-18 | — | — | EP | disclosed |
| EP-0775698-A1 | Bis-resorcinol-triazines as UV absorber triazine | Ciba SC Holding AG (CH) | 1997-05-28 | — | — | EP | disclosed |
| US-5095113-A | Preparation of methyl-1,3-5-triazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0051067-A1 | TRIAZINE SYNTHESIS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-05-12 | — | — | EP | disclosed |
| WO-1981003020-A1 | TRIAZINE SYNTHESIS | COMMW SCIENT IND RES ORG (AU) | 1981-10-29 | — | — | WO | disclosed |
| JP-S5610175-A | PREPARATION OF IMIDAZOLE DERIVATIVE | FUJISAWA PHARMACEUT CO LTD | 1981-02-02 | — | — | JP | disclosed |