Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | KLK7 | P49862 | 4/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | CDC25A | P30304 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171071 | 1.00 | PPARA (0.50) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL13537921 | 0.82 | KLK7 (0.59) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL13537920 | 0.82 | KLK7 (0.59) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL8184799 | 0.81 | PPARA (0.41) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL4807967 | 0.80 | NPSR1 (0.39) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL8171835 | 0.79 | PPARA (0.39) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL4746758 | 0.78 | HTT (0.44) | MEN1KMT2A | |
| SCHEMBL3975545 | 0.78 | HTT (0.44) | MEN1KMT2A | |
| SCHEMBL9296151 | 0.78 | ATM (0.47) | KLK5CTSSCTSLMEN1KMT2A | |
| SCHEMBL4042099 | 0.77 | ATM (0.48) | KLK5CTSSCTSLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107365-A1 | NEW COMPOUNDS | MEDIVIR AB (SE) | 2008-09-12 | — | — | WO | disclosed |