SCHEMBL4803528

SCHEMBL4803528

CC(C)=CI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6422570 0.74
SCHEMBL15368904 0.74
SCHEMBL14877984 0.70
SCHEMBL13888882 0.70
SCHEMBL11036355 0.70
SCHEMBL51629 0.67
SCHEMBL23140247 0.65
SCHEMBL7642778 0.63
Water SCHEMBL20487245 0.63
Phosphine SCHEMBL31567941 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109438218-A A kind of hydrochloric acid Ai Le replaces the synthetic method of Buddhist nun's intermediate 2- (4- ethyl -3- iodophenyl) -2 Methylpropionic acid 成都艾必克医药科技有限公司 2019-03-08 CN claimed
US-6603013-B2 Heterogeneous palladium catalyst and a base in an aprotic solvent; for use with either electron-withdrawing or electron-donating substituents MERCK & CO., INC. 2003-08-05 US claimed
US-20020045775-A1 Heterogeneously catalyzed process for cross coupling alkenyl halides with boronic acids MERCK & CO., INC. 2002-04-18 US claimed
CN-109438218-A A kind of hydrochloric acid Ai Le replaces the synthetic method of Buddhist nun's intermediate 2- (4- ethyl -3- iodophenyl) -2 Methylpropionic acid 成都艾必克医药科技有限公司 2019-03-08 CN disclosed
US-20170288053-A1 SEMICONDUCTOR DEVICE RENESAS ELECTRONICS CORPORATION (JP) 2017-10-05 US disclosed
US-20170261475-A1 APPARATUS AND METHOD FOR MITIGATION OF ALTERATIONS IN MASS SPECTROMETRY IN THE PRESENCE OF HYDROGEN CISTERNI MARCO (IT) 2017-09-14 US disclosed
US-9622989-B2 Treatment of osteoporosis HAOMA MEDICA LIMITED (GB) 2017-04-18 US disclosed
US-20170008873-A1 COT MODULATORS AND METHODS OF USE THEREOF GILEAD SCIENCES, INC. 2017-01-12 US disclosed
US-9540386-B2 Crystals of dispiropyrrolidine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-01-10 US disclosed
US-9085803-B2 Probe for detection of polymorphism in ABL gene, and use thereof ARKRAY, INC. (KR) 2015-07-21 US disclosed
WO-2014209980-A1 PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF MERCK PATENT GMBH (DE) 2014-12-31 WO disclosed
WO-2004013094-A2 COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2004-02-12 WO disclosed
US-6603013-B2 Heterogeneous palladium catalyst and a base in an aprotic solvent; for use with either electron-withdrawing or electron-donating substituents MERCK & CO., INC. 2003-08-05 US disclosed
EP-0919870-B1 Photosensitive resin composition and photosensitive element using the resin composition NICHIGO MORTON CO LTD (JP) 2002-07-03 EP disclosed
US-20020045775-A1 Heterogeneously catalyzed process for cross coupling alkenyl halides with boronic acids MERCK & CO., INC. 2002-04-18 US disclosed
US-6242158-B1 POLYMER WITH CARBOXY DERIVATIVES, ETHYLENE AND ACRYLIC ESTER DERIVATIVES NICHIGO-MORTON CO., LTD. (JP) 2001-06-05 US disclosed
EP-0919870-A1 Photosensitive resin composition and photosensitive element using the resin composition Nichigo-Morton Co Ltd (JP) 1999-06-02 EP disclosed
US-4593096-A Novel compounds and process for treating hypertension THE UPJOHN COMPANY (US) 1986-06-03 US disclosed
US-4460589-A 2-AMINO-5-HALO-6-PHENYL-4-PYRIMIDINONES THE UPJOHN COMPANY (US) 1984-07-17 US disclosed
US-4175187-A REACTING ETHYLENE, SUBSTITUTED ETHYLENE WITH A SECONDARY AMINE AND A PALLADIUM CATALYST UNIVERSITY OF DELAWARE (US) 1979-11-20 US disclosed