SCHEMBL4804468

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7247899	0.86	DRD4 (0.76)	DRD4DRD2KDM4EALDH1A1CYP3A4
	SCHEMBL4812823	0.86	DRD4 (1.00)	DRD4DRD2KDM4EALDH1A1CYP3A4
	SCHEMBL14786712	0.84	PARP1 (0.69)	DRD4KDM4EALDH1A1GAA
	SCHEMBL4807109	0.83	DRD4 (1.00)	DRD4DRD2KDM4EALDH1A1CYP3A4
	SCHEMBL4809160	0.83	DRD4 (1.00)	DRD4DRD2KDM4EALDH1A1CYP3A4
	SCHEMBL4810310	0.81	DRD4 (0.74)	DRD4DRD2KDM4EALDH1A1CYP3A4
	SCHEMBL5157052	0.81	HTT (0.84)	DRD4DRD2KDM4EALDH1A1CYP3A4
	Abt-724 SCHEMBL1448486	0.81	DRD4 (1.00)	DRD4DRD2KDM4EALDH1A1CYP3A4
	Abt-724 SCHEMBL29406160	0.81	DRD4 (1.00)	DRD4DRD2KDM4EALDH1A1CYP3A4
	SCHEMBL23964267	0.81	USP2 (0.64)	DRD4DRD2KDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.